Animal Free Research UK

Registered charity 1146896 · since 2012animalfreeresearchuk.org·Exeter, Keele, Liverpool, Nottingham, Sheffield·Updated 30 October 2026

At a glance

£290k
Annual giving, year to 31 March 2025
From filed accounts
£14,500 to £47,000
Grant range
From the annual report's grant list
£22,263
Typical grant (median)
8 published grants
Open to applications
Fixed application deadlines · unsolicited applications welcome

Key takeaways

  • Animal Free Research UK fits projects that replace animal use with human-focused methods, and its named areas are cancer, cardiovascular disease, neurodegenerative disease and toxicology, though it says other projects are considered too.
  • Its typical grants fall around £14,500 to £47,000, with a median of about £22,000, and its Pilot & Transition grants are stated at £5,000 to £25,000, so a request in that lower band matches the stated programme sizes.
  • Only researchers in universities, hospitals, research organisations or industry, including contract research organisations, can apply, and for Pilot calls the primary applicant is expected to have tenure or an open-ended permanent post, so a charity without such a researcher should not apply in its own name.
  • Transition grants do not cover animal-derived biomaterials, and applicants must use the Pilot or Transition form before each call's closing deadline.
  • No geographic area is stated as a condition; the annual report shows grants mainly in Nottingham, Sheffield, Liverpool, Exeter and Keele, but that is not a rule about who may apply.

Overview

Animal Free Research UK is a charity registered with the Charity Commission for England and Wales (charity number 1146896).

Animal Free Research UK is a charity registered with the Charity Commission for England and Wales (charity number 1146896) that funds research developing human-focused technologies as replacements for animal experiments. Its mission is to champion animal-free, human-specific technologies that deliver better treatments for human diseases faster. It runs Pilot grants, which let researchers explore replacement ideas and gather data to help secure further funding, and Transition grants, which support scientists moving from animal research to animal-free research. It says it has given £10M in grants to projects including those on cancer, diabetes and Covid-19, and its annual report shows £290,003 paid in its most recent reported year.

What they fund

Priority Areas

Animal Free Research UK funds research developing human-focused technologies as replacements for animal experiments, with projects directly relevant to biomedical research and human health. Pilot grants help researchers explore replacement-science ideas and gather data to support applications for further funding; Transition grants support scientists moving from animal-based research to animal-free approaches. Researchers in universities, hospitals, research organisations and industry, including contract research organisations, can apply. Its named focus areas are cancer, cardiovascular disease, neurodegenerative disease and toxicology, although projects outside these areas are also considered. Selection considers the potential to replace animal use, scientific merit and innovation, researchers’ expertise, feasibility and value to the wider scientific community.

Themes

  • Animal-free research
  • Cancer
  • Cardiovascular disease
  • Neurodegenerative disease
  • Toxicology

Geographic Focus

No geographic focus is stated; the annual report shows grants mainly in Nottingham, Sheffield, Liverpool, Exeter and Keele.

What they don't fund

  • Transition grants only: Animal-derived biomaterials (ADBs) will not be covered by the grant

How to apply

Applicants complete either the Pilot Grant Application Form or the Transition Grant Application Form.

Deadlines: A closing deadline is set for each grant call.

Who can apply:

  • Pilot & Transition Grants: Researchers in universities, hospitals, research organisations and industries including contract research organisations are eligible to apply.
  • Pilot Study grant call: The primary applicant is expected to have tenure or an open-ended permanent contract/position.

Application success factors

What the charity says:

  • The foundation particularly welcomes researchers moving from animal-based methods to relevant animal-free, human-focused approaches.
  • Requests are assessed for animal-replacement potential and alignment with its strategic goals.
  • It considers scientific merit and innovation.
  • It considers the grant holder’s and project group’s expertise, experience and publication record.
  • It considers feasibility, implementation, resources, budgeting and outputs.
  • It considers the research’s merit to the wider scientific community and its dissemination plan.

Where they fund

Where its grants have gone

  • Exeter
  • Keele
  • Liverpool
  • Nottingham
  • Sheffield

Similar funders

Funders supporting work similar to Animal Free Research UK.

Grants

8 published grants analysed · median £22,263

How much do they typically give?

Share of 8 grants in year to 31 March 2025 by size

£10k–£25k63%
£25k–£50k38%

Median £22,263 (year to 31 March 2025)

The largest grants to organisations in this funder’s latest annual report:

  • Nottingham Trent University
    £46,902year to 31 March 2025
  • Edge Hill University
    £25,000year to 31 March 2025
  • University of Liverpool
    £25,000year to 31 March 2025
  • University of Exeter
    £22,476year to 31 March 2025
  • Sheffield Hallam University
    £22,049year to 31 March 2025
  • University of Sheffield
    £19,778year to 31 March 2025
  • Keele University
    £18,600year to 31 March 2025
  • University College London
    £14,500year to 31 March 2025

Grant examples taken from the funder’s filed accounts.

Five years of accounts

Financial yearIncomeExpenditureGrants paidAccounts document
year to 31 March 2021£1,505,965£720,166£55,255Accounts for year to 31 March 2021
year to 31 March 2022£1,408,763£1,049,058£124,348Accounts for year to 31 March 2022
year to 31 March 2023£1,539,316£1,397,250£358,524Accounts for year to 31 March 2023
year to 31 March 2024£1,445,123£1,319,007£154,778Accounts for year to 31 March 2024
year to 31 March 2025£1,035,302£1,473,935£290,003Accounts for year to 31 March 2025

Income vs grants paid

IncomeGrants paid

Total value each financial year

YE 2021
£55,255 grants
YE 2022
£124k grants
YE 2023
£359k grants
YE 2024
£155k grants
YE 2025
£290k paid

Grants paid stayed within income across the 5 years shown.

  • Grants paid, year to 31 March 2021; year to 31 March 2022; year to 31 March 2023; year to 31 March 2024: grants to institutions, as reported on the charity register (Part B).
  • Grants paid, year to 31 March 2025: grants paid out in the year.

Figures from the charity’s filed accounts and its register entry. The document icon links to the charity’s entry on the Charity Commission register, where its filed accounts can be found.

Sources

  • Annual report (year to 31 March 2025)

This profile draws on the funder’s own website as well as its filed accounts.

Sources last checked on 30 October 2026.

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