Replacing Animal Research
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Quick Stats
- Annual Giving: £242,510 (2022-2023)
- Success Rate: Not publicly available
- Decision Time: Not publicly available
- Grant Range: Not publicly specified
- Geographic Focus: UK-based, international reach
Contact Details
- Website: https://replacinganimalresearch.org.uk/
- Phone: +44 (0)115 958 4740
- Email: hello@replacinganimalresearch.org.uk
- Address: Cawley House, 149-155 Canal Street, Nottingham NG1 7HR, UK
- For Scientists: Visit the “For Scientists” section on their website for funding opportunities
Overview
Replacing Animal Research, originally known as FRAME (Fund for the Replacement of Animals in Medical Experiments), was founded in 1969 by Dorothy Hegarty. With the mission “We believe in a future where no animal suffers for science,” the charity champions non-animal research methods and funds human-relevant research. In 2022-2023, they distributed £242,510 in research funding to scientists developing alternative research methods. The organization focuses on collaborating with and educating scientists while influencing policy to reduce animal testing across the scientific community.
Funding Priorities
Grant Programs
- Innovation Grant Scheme: Funding for researchers developing non-animal research methods (amounts not publicly specified)
- Summer Studentship Programme: Support for students conducting research on alternatives to animal testing
Priority Areas
The organization funds research in the following areas:
- Brain research
- Cancer
- Diabetes
- Gut Health
- Heart disease
- Infection
- Liver research
- Lungs
- Metabolism
- Musculoskeletal conditions
What They Fund
- Development of non-animal research methods
- Projects that help replace animal use in testing and research
- Research that advances scientific methods to replace animal use
- Skills development in human-based research methods and science communication
What They Don't Fund
Specific exclusions are not publicly listed on their website

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Governance and Leadership
Leadership details are not prominently displayed on their public website. The organization operates from their headquarters in Nottingham, UK.
How to Apply to Replacing Animal Research
How to Apply
Scientists and researchers can apply for grants through their website. Applications should be submitted through the “For Scientists” section. The organization recommends reviewing their Grant Funding Policy 2025 document for comprehensive information about their funding approach.
Decision Timeline
Decision timelines are not publicly specified
Success Rates
Success rate data is not publicly available
Reapplication Policy
Reapplication policies are not publicly specified
Application Success Factors
Based on the organization's mission and funding focus, successful applications likely demonstrate:
- Clear alignment with replacing animal research methods
- Scientific rigor in developing alternative methodologies
- Potential for widespread adoption of the alternative methods
- Contribution to the 3Rs principle (Replacement, Reduction, Refinement)
- Innovation in human-relevant research approaches
The organization emphasizes supporting researchers at “every stage of your career,” suggesting they welcome applications from both early-career and established researchers.
Key Takeaways for Grant Writers
- Focus on demonstrating how your research directly replaces or reduces animal use in scientific research
- Emphasize the human relevance and translational potential of your alternative methods
- Consider applying for the Summer Studentship Programme if you're an early-career researcher
- Align your proposal with one or more of their ten priority research areas
- Highlight any potential for your research to influence policy or practice in reducing animal testing
- Contact the organization directly for specific application guidance as detailed requirements are not publicly available
Similar Funders
These funders have a similar focus and geographic reach:
- The Frances And Augustus Newman Foundation
- The Humane Research Trust
- The Beryl Evetts And Robert Luff Animal Welfare Trust Limited
- The Humane Research Trust Cio
- John Innes Foundation
- The Michael Uren Foundation
- Bma Foundation
- Against Breast Cancer Limited
- The Anthony V Martin Charitable Foundation
- Matthew Good Foundation
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References
- Replacing Animal Research official website (https://replacinganimalresearch.org.uk/) -
- For Scientists funding page (https://replacinganimalresearch.org.uk/for-scientists/) -
- Organization homepage and mission statement (http://www.replacinganimalresearch.org.uk/) -
- Annual giving figure of £242,510 for 2022-2023 from organization website
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