Manning Family Foundation
At a glance
Key takeaways
- The Manning Family Foundation, based in Charlottesville, Virginia, funds two areas: health and life sciences research aimed at more effective treatments and cures, and local giving to groups in Charlottesville, Virginia that share its vision of a thriving community.
- For most applicants a modest request fits best, as half of its 182 grants were $25,000 or less and about eight in ten fell between $4,550 and $300,000, although it can occasionally make a much larger grant, such as one to an organisation that itself regrants to other organisations.
- It accepts applications on a rolling basis, and first-time applicants, or those who have not received funding in over two years, should begin with a brief letter of inquiry before submitting a full application.
- Just under half of its grant dollars to organisations (47%) went to groups it had also funded in the two previous filings, suggesting a strong but not exclusive pattern of repeat support, so new applicants whose work fits one of its two focus areas should still feel able to approach it.
- Proposals should clearly show valuable work in one of the foundation's two philanthropic focus areas.
Overview
Manning Family Foundation is a US private foundation based in Charlottesville, VA.
What they fund
Profile derived from the foundation's IRS Form 990-PF filings (TY2024, TY2023, TY2022) and its website, with every statement checked against those sources. Sources read on 7 October 2026.
Priority Areas
The foundation focuses on two areas. In health and life sciences research, it supports research that leads to the development of more effective treatments and ultimately cures for the world’s most disruptive diseases, encouraging a spirit of entrepreneurialism. Its local giving supports groups in Charlottesville, Virginia that share its vision of a thriving community, where culture can flourish and families can prosper. It makes grants to 501(c)(3) nonprofits whose work is valuable in these focus areas. Its approach connects its grants to those focus areas and encourages entrepreneurialism in research.
Themes
- Health & Life Sciences Research
- Local Giving
Geographic Focus
Charlottesville, Virginia.
How to apply
First-time applicants and grantees who have not received funding in over two years submit a brief letter of inquiry before submitting an application.
Application success factors
- Repeat giving: In its TY2024 filing, 47% of its grant dollars to organisations went to organisations it had also funded in its TY2022 or TY2023 filing.
- Grant size: Across its TY2022, TY2023 and TY2024 filings, half of its 182 grants to organisations were $25,000 or less.
What the foundation says:
- Proposals should show valuable work in one of the foundation’s two philanthropic focus areas.
- Grantees submit an annual progress report through the web portal.
Where grants go
From grants to organisations in the foundation’s filings for tax years 2022–2024.
Grant dollars by state
4 other states: <1%
- The largest single recipient received 18% of grant dollars to organisations.
- In tax year 2024, 47% of grant dollars went to organisations Manning Family Foundation had funded in earlier filings.
- No grants were paid directly to organisations outside the US.
- 46% of grant dollars went to intermediaries that regrant to other organisations.
Grants
How much do they typically give?
Share of 65 grants in tax year 2024 by size
Median $25,000 (tax year 2024)
The largest grants to organisations in the foundation’s latest filing:
- Fidelity Charitable · General$4,800,0002024 tax year
- University of Virginia Health Foundation · General$3,060,0002024 tax year
- Breakthrough T1D · General$1,500,0002024 tax year
- University of Massachusetts · General$1,000,0002024 tax year
- Duke University · General$304,0002024 tax year
- Affordable Housing Opportunity Fund · General$300,0002024 tax year
- Charlottesville BioHub · General$255,0002024 tax year
- The Red Sox Foundation · General$250,0002024 tax year
Grants to organisations listed in the foundation’s Form 990-PF filings. Grants to individuals are not shown.
Officers and directors
- Russell T Schundler — Secretary
- Kaitlyn M Henry — Director
- Bryan P Manning — Director
- Bradford J Manning — Director
- Diane L Manning — Director and Secretary
- Paul B Manning — Director, President, Treasurer
From the latest Form 990-PF filing
3 years of tax filings
| Year | Total expenses | Grants paid | Assets | Filing document |
|---|---|---|---|---|
| 2022 tax year | $15,909,141 | $14,646,035 | $253,756,007 | Filing for 2022 tax year |
| 2023 tax year | $14,634,604 | $13,435,740 | $274,981,200 | Filing for 2023 tax year |
| 2024 tax year | $14,263,739 | $13,517,558 | $302,402,755 | Filing for 2024 tax year |
Figures from the foundation’s IRS Form 990-PF filings. Assets are at fair market value at year end. The document icon links to each year’s filing on ProPublica Nonprofit Explorer.
Sources
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At a glance

Applying to Manning Family Foundation?
Hinchilla drafts your answers around this funder's priorities, using your organisation's own documents.
No credit card required
Contact
- (434) 980-8142
- heidi@themanningfamilyfoundation.org
- HEIDI@THEMANNINGFAMILYFOUNDATION.ORG
- Charlottesville, VA
- themanningfamilyfoundation.org

Applying to Manning Family Foundation?
Hinchilla drafts your answers around this funder's priorities, using your organisation's own documents.
No credit card required
Contact
- (434) 980-8142
- heidi@themanningfamilyfoundation.org
- HEIDI@THEMANNINGFAMILYFOUNDATION.ORG
- Charlottesville, VA
- themanningfamilyfoundation.org