Histiocytosis Uk

Charity Number: 1158789

Annual Expenditure: £0.1M

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Quick Stats

  • Annual Giving: £133,154 (total expenditure 2024)
  • Success Rate: Not available
  • Decision Time: Variable (depends on next Trustee Board meeting)
  • Grant Range: Up to £50,000
  • Geographic Focus: UK-based research

Contact Details

Overview

Histiocytosis UK (Charity Number: 1158789) is a specialized medical research charity dedicated to funding scientific research into histiocytic diseases, including Langerhans Cell Histiocytosis (LCH) and Haemophagocytic Lymphohistiocytosis (HLH). Formed in 2015 through the amalgamation with The Histiocytosis Research Trust, the charity operates with an annual income of approximately £128,548 (2024) and focuses on promoting research that leads to early diagnosis, effective treatment, and ultimately a cure for these rare conditions. The organization maintains a distinguished Scientific Review Board that includes Nobel Prize winner Prof Ralph Steinman's legacy and employs a rigorous peer review system for grant applications.

Funding Priorities

Grant Programs

  • Research Project Grants: Up to £50,000 over 24 months
  • Applications accepted via online portal or downloadable form
  • Focus on paediatric Langerhans Cell Histiocytosis and HLH research
  • Funds salaries and consumables for researchers

Priority Areas

  • Epidemiology, pathogenesis, diagnosis, treatment, and clinical care of histiocytic disorders
  • Studies into Histiocytic Neoplasms (LCH and rare types)
  • Haemophagocytic Lymphohistiocytosis (HLH) research
  • Development of more accurate diagnostic methods
  • Improved protocols for patient management
  • Prevention measures for histiocytic diseases

What They Don't Fund

  • Principal Investigator salary
  • Institutional overheads
  • IT equipment
  • Travel expenses
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Governance and Leadership

Scientific Review Board Leadership:

  • Chair: Professor Matthew Collin BM, BCh, DPhil, MRCP, FRCPath (appointed 2014)
  • Oxford University Medical School graduate, Consultant Haematologist since 2006
  • Vice-Chair: Professor Peter Beverley MBBS, DSc, FmedSci
  • Trustee since inception, specialist in immunology

Specialized Review Boards:

LCH/Neoplastic Board:

  • Barrett Rollins MD, PhD
  • Carl Allen MD, PhD
  • Florent Ginhoux MD, PhD
  • Ely Diamond MD

HLH Board:

  • Michael Jordan MD
  • Yenan Bryceson PhD
  • Mike Dustin PhD
  • Rob Wynn MA MD MRCP FRCPath

The charity operates with 5 Trustees and 2 volunteers, with no trustees receiving remuneration.

Application Process and Timeline

How to Apply

Two application options available:

  • Pre-type application in draft form recommended
  • System does not have auto-save functionality
  • Confirmation copy sent to applicant upon submission
  • Available from the downloads section of their website

Required documentation:

  • Research Grant Guidelines
  • Project Grant Terms and Conditions

Decision Timeline

  • Applications reviewed by Scientific Review Board using peer review system
  • Recommendations submitted to Trustees at next available Board meeting
  • Timeline varies depending on Board meeting schedule

Success Rates

Not publicly available

Reapplication Policy

Not specified in available documentation

Application Success Factors

Based on Histio UK's funding criteria and review process:

  • Research Impact: Clearly describe the likely impact of research on patients with histiocytic disorders
  • Leverage Potential: Outline a plan to attract further independent funding using the award as a catalyst
  • Scientific Merit: Projects undergo rigorous peer review by specialists in LCH/Neoplastic or HLH fields
  • Alignment: Focus specifically on paediatric Langerhans Cell Histiocytosis or HLH
  • Budget Justification: Ensure costs align with eligible expenses (salaries and consumables only)

Key Takeaways for Grant Writers

  • Maximum grant of £50,000 over 24 months represents significant funding for specialized research
  • Strong emphasis on translational impact - must demonstrate clear benefit to patients
  • Requirement to leverage funding for additional grants shows focus on sustainability
  • Specialized review boards mean applications are evaluated by true subject matter experts
  • Limited eligible costs require careful budget planning
  • Partnership approach evident through collaboration with MRC-funded HistioNode Research Project

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References