Lopker Family Foundation
At a glance
Key takeaways
- The Lopker Family Foundation funds translational cancer research that moves promising laboratory discoveries toward first-in-human clinical trials, so a nonprofit whose work sits outside that area is unlikely to fit.
- The foundation describes its partners as public universities whose cancer research centres are NCI-designated comprehensive cancer centres, and it prioritises institutions that lead in innovation despite smaller unrestricted endowments, so an organisation that is not such an institution should check its fit before writing in.
- Half of its grants to organisations were $10,000 or less, so a modest request is the realistic starting point, although one award of $1,000,000 appears above its stated $200,000 to $300,000 grant range.
- The filing shows that 92% of its grant dollars went to organisations it had also funded in an earlier filing, so this looks like a relationship-led funder, and a first approach should be a letter naming the organisation and grant purpose, with a copy of its federal tax-exemption letter.
- The filing gives no deadlines, so no set date for applications is stated.
Overview
Lopker Family Foundation is a US private foundation based in Santa Barbara, CA.
What they fund
Profile derived from the foundation's IRS Form 990-PF filings (TY2024, TY2023, TY2022) and its website, with every statement checked against those sources. Sources read on 7 October 2026.
Priority Areas
The Lopker Family Foundation funds translational cancer research, aiming to move promising laboratory discoveries through the gap between academic discovery and first-in-human clinical trials. Its support covers safety and efficacy studies, pre-IND and IND regulatory milestones, clinical readiness, novel drug combinations and breakthrough diagnostics. It partners with public universities whose cancer research centres are NCI-designated comprehensive cancer centres, prioritising institutions that lead in innovation despite having smaller unrestricted endowments than their private counterparts. Projects are vetted by a board of volunteer scientists for technical merit and clinical viability. The foundation seeks to maximise capital working in the lab to bring cancer cures to market quickly.
Themes
- Cancer research
Geographic Focus
No geographic focus is stated; the filings show grants mainly in Washington and California.
How to apply
Submit an application letter naming the organisation and grant purpose, with a copy of the organisation's federal tax-exemption letter.
Application success factors
- Repeat giving: In its TY2024 filing, 92% of its grant dollars to organisations went to organisations it had also funded in its TY2022 or TY2023 filing.
- Grant size: Across its TY2022, TY2023 and TY2024 filings, half of its 98 grants to organisations were $10,000 or less.
What the foundation says:
- It partners with public universities whose cancer research is at NCI-designated comprehensive cancer centres.
- It prioritises institutions that lead in innovation despite having smaller unrestricted endowments than their private counterparts.
- Projects are vetted by a board of volunteer scientists for technical merit and clinical viability.
Where grants go
From grants to organisations in the foundation’s filings for tax years 2022–2024.
Grant dollars by state
2 other states: <1%
- The largest single recipient received 23% of grant dollars to organisations.
- In tax year 2024, 92% of grant dollars went to organisations Lopker Family Foundation had funded in earlier filings.
- <1% of grant dollars went directly to organisations outside the US (Canada).
- 6% of grant dollars went to intermediaries that regrant to other organisations.
Grants
How much do they typically give?
Share of 32 grants in tax year 2024 by size
Median $7,530 (tax year 2024)
The largest grants to organisations in the foundation’s latest filing:
- Fred Hutchinson Cancer Center · Multi department donation$1,000,0002024 tax year
- UCLA Jonsson Cancer Center Foundation · Dr slamon cancer research$750,0002024 tax year
- Totem Technologies · In furtherance of section 501 (c)(3) exempt purpose$150,0002024 tax year
- Giving What We Can · In furtherance of section 501 (c)(3) exempt purpose$140,0002024 tax year
- Scholarship Foundation Of SB · Karl lopker memorial endowed scholarship fund$100,0002024 tax year
- University of Washington Foundation · Allergy & infectious diseases parasitology fund$100,0002024 tax year
- University of Washington Foundation · Institute for prostate cancer research fund$100,0002024 tax year
- The Life You Can Save · In furtherance of section 501 (c)(3) exempt purpose$50,0002024 tax year
Grants to organisations listed in the foundation’s Form 990-PF filings. Grants to individuals are not shown.
Officers and directors
- Anita H Blakemore — Secretary / CFO
- Juliana L Lopker — Vice President
- Karl Bo Lopker — Vice President
- Pamela M Lopker — President / CEO
From the latest Form 990-PF filing
3 years of tax filings
| Year | Total expenses | Grants paid | Assets | Filing document |
|---|---|---|---|---|
| 2022 tax year | $4,136,901 | $2,897,000 | $64,219,473 | Filing for 2022 tax year |
| 2023 tax year | $3,886,640 | $3,232,983 | $66,288,739 | Filing for 2023 tax year |
| 2024 tax year | $3,182,951 | $2,627,744 | $69,625,315 | Filing for 2024 tax year |
Figures from the foundation’s IRS Form 990-PF filings. Assets are at fair market value at year end. The document icon links to each year’s filing on ProPublica Nonprofit Explorer.
Sources
Registers and filings
Other sources
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At a glance

Applying to Lopker Family Foundation?
Hinchilla drafts your answers around this funder's priorities, using your organisation's own documents.
No credit card required
Contact
- (805) 684-6641
- foundation@lopker.net
- Santa Barbara, CA
- lopker.net

Applying to Lopker Family Foundation?
Hinchilla drafts your answers around this funder's priorities, using your organisation's own documents.
No credit card required
Contact
- (805) 684-6641
- foundation@lopker.net
- Santa Barbara, CA
- lopker.net