Regenstrief Foundation

Private foundation · EIN 35-6066023 · since 1967regfdn.org·United States·Updated 13 October 2026

At a glance

$8.2M
Annual giving, 2024 tax year
From the Form 990-PF filing
$5,000 to $6.8M
Grant range
From grants in the 990-PF filings
$708k
Typical grant (median)
4 grants in the latest filing
Open to applications
Rolling, no deadlines · unsolicited applications welcome

Key takeaways

  • Regenstrief Foundation funds applied, practical health-care research in areas such as informatics and data analytics, dissemination and implementation, epidemiology, and engineering in health care, so it suits research-performing organisations whose work clearly aligns with these themes.
  • Its geographic focus is the United States.
  • Typical grants to organisations run from $5,000 to $6,750,000, but half of its 13 grants were $10,000 or less, so a modest request fits the usual pattern even though larger awards do occur.
  • The foundation does not accept unsolicited proposals; it only invites applications from organisations whose work clearly aligns with its priorities, so first make contact through its Contact Us form before preparing a proposal.
  • It accepts applications on a rolling basis, and 99% of its grant dollars to organisations went to organisations it had also funded in the two prior filings, suggesting it is strongly relationship-led and favours continuing, deep engagement with grantees, including frequent meetings and sometimes board or committee service, so new applicants should expect this to be a long-term relationship rather than a one-off grant.

Overview

Regenstrief Foundation is a US private foundation based in Indianapolis, IN.

What they fund

Profile derived from the foundation's IRS Form 990-PF filings (TY2024, TY2023, TY2022) and its website, with every statement checked against those sources. Sources read on 7 October 2026.

Priority Areas

The foundation supports innovative, applied research to make health-care systems more effective and efficient and to improve quality and equity in care. It prioritises practical research that develops real-world, implementable solutions for health-care delivery and accessibility. Its stated impact areas include informatics and data analytics, dissemination and implementation of transformative processes, epidemiology, and applying engineering principles to health care. It identifies goals for measuring each research project's impact and seeks deep, long-lasting relationships with grantees, including frequent meetings and, at times, board or committee service. It may also provide operational support to help grantee institutions remain stable. It supports research-performing grantees and describes its geographic scope as not restricted within the United States.

Themes

  • Informatics and data analytics
  • Dissemination and implementation
  • Epidemiology
  • Engineering in health care

Geographic Focus

United States.

How to apply

Organisations that think their work aligns with the foundation’s priorities should first contact it through the Contact Us form. It does not accept unsolicited proposals and invites applications only from organisations whose work clearly aligns.

Application success factors

  • Repeat giving: In its TY2024 filing, 99% of its grant dollars to organisations went to organisations it had also funded in its TY2022 or TY2023 filing.
  • Grant size: Across its TY2022, TY2023 and TY2024 filings, half of its 13 grants to organisations were $10,000 or less.

What the foundation says:

  • It prioritises practical research that develops real-world, implementable solutions for health-care delivery and accessibility.
  • It identifies specific goals in the application to measure each research project's impact.
  • It seeks deep, long-lasting relationships with grantees, meeting frequently with grant recipients and sometimes serving on their boards or committees.

Where grants go

From grants to organisations in the foundation’s filings for tax years 2022–2024.

Grant dollars by state

Indiana100%
District of Columbia<1%
  • The largest single recipient received 84% of grant dollars to organisations.
  • In tax year 2024, 100% of grant dollars went to organisations Regenstrief Foundation had funded in earlier filings.
  • No grants were paid directly to organisations outside the US.

Grants

4 grants in the latest filing analysed · median $708k

The largest grants to organisations in the foundation’s latest filing:

  • Regenstrief Institute · Medical research
    $6,749,0462024 tax year
  • Eskenazi Health Foundation · Medical research
    $1,410,5782024 tax year
  • Dove Recovery House · Medical research
    $5,0002024 tax year
  • American Speech-Language Grant · Medical research
    $5,0002024 tax year

Grants to organisations listed in the foundation’s Form 990-PF filings. Grants to individuals are not shown.

Officers and directors

  • Eli Isaacs (Beg 040925) — Volunteer Director
  • Jamie Rich — Volunteer Director
  • Christia Hicks — Volunteer Director
  • Allison Barrett (THRU 021925) — Volunteer Director
  • Enola Proctor — Volunteer Director
  • James Tcheng — Volunteer Director
  • Latoya Botteron — Volunteer Director
  • Andie Friedman — Investment Committee Chair
  • Daniel Appel — Chairman
  • Lesley B Olswang PHD (Thru 040125) — Volunteer Director
  • Bob Wingerter — Vice President & Treasurer
  • D Craig Brater — President & Director
  • Susan Luse — Secretary

From the latest Form 990-PF filing

3 years of tax filings

YearTotal expensesGrants paidAssetsFiling document
2022 tax year$12,522,574$9,416,000$176,164,818Filing for 2022 tax year
2023 tax year$10,500,149$7,613,421$182,349,778Filing for 2023 tax year
2024 tax year$11,220,711$8,169,624$189,717,469Filing for 2024 tax year

Figures from the foundation’s IRS Form 990-PF filings. Assets are at fair market value at year end. The document icon links to each year’s filing on ProPublica Nonprofit Explorer.

Sources

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