ALS Finding a Cure®

Private foundation · EIN 30-6068334 · since 2004alsfindingacure.org·California, District of Columbia, Florida, International, Massachusetts, Texas·Updated 13 October 2026

At a glance

$7.3M
Annual giving, 2025 tax year
From the Form 990-PF filing
$2,500 to $200k
Grant range
From grants in the 990-PF filings
$25,000
Typical grant (median)
88 grants in the latest filing
Open to applications
Rolling, no deadlines · unsolicited applications welcome

Key takeaways

  • ALS Finding a Cure's sole purpose is to fund research to find a cure for ALS, so work outside that aim is unlikely to fit, and its research calls are open to investigators at academic, clinical and research institutions worldwide.
  • Most of its grants to organisations are modest: about 8 in 10 of its 304 fall between $2,500 and $200,000, half are $25,000 or less, and the median is $25,000, so a modest request fits, although the largest grant was $2,000,000 and that band is not a ceiling.
  • Start with a Letter of Intent, since only selected applicants are invited to submit a full proposal, and note that the foundation accepts applications on a rolling basis.
  • The filing shows that 69% of its grant dollars to organisations went to organisations it had also funded before, so repeat funding carries real weight, and your proposal should address the foundation's stated criteria of innovation, relevance to ALS onset biology, translational potential, team complementarity, feasibility and milestones, and the cross-institutional, multidisciplinary teams it encourages.

Overview

ALS Finding a Cure® is a US private foundation based in Boynton Beach, FL.

What they fund

Profile derived from the foundation's IRS Form 990-PF filings (TY2025, TY2024, TY2023) and its website, with every statement checked against those sources. Sources read on 7 October 2026.

Priority Areas

The foundation’s sole purpose is to fund research to find a cure for ALS. It aims to bring together some of the top minds in ALS to develop novel biomarkers and diagnostics, advance new therapies towards the clinic, improve clinical-trial design and expand access to shared research resources. Its stated principles are to invest in shared challenges and new technologies, partner and collaborate, pool and share data, and ensure every study informs progress towards a cure. Its research calls are open to investigators at academic, clinical and research institutions worldwide, and it encourages multidisciplinary, cross-institutional teams.

Themes

  • ALS biomarkers and diagnostics
  • ALS therapies
  • Clinical trial design
  • Shared research resources

Geographic Focus

Priority: Worldwide. From its grants, not stated by the foundation: Florida; California; Massachusetts; Texas; District of Columbia.

How to apply

Applicants submit a Letter of Intent first; selected applicants are invited to submit a full proposal.

Application success factors

  • Repeat giving: In its TY2025 filing, 69% of its grant dollars to organisations went to organisations it had also funded in its TY2023 or TY2024 filing.
  • Grant size: Across its TY2023, TY2024 and TY2025 filings, half of its 304 grants to organisations were $25,000 or less.

What the foundation says:

  • It particularly values high-risk, high-reward ideas capable of shifting current paradigms.
  • It assesses proposals for innovation, relevance to ALS onset biology, translational potential, team complementarity, feasibility and milestones.
  • It encourages cross-institutional and multidisciplinary teams.

Where grants go

From grants to organisations in the foundation’s filings for tax years 2023–2025.

Grant dollars by state

Florida19%
California18%
Massachusetts10%
Texas9%
District of Columbia8%
Louisiana8%

6 other states: 20%

Outside the US or with no state on the filing: 7%

  • The largest single recipient received 13% of grant dollars to organisations.
  • In tax year 2025, 69% of grant dollars went to organisations ALS Finding a Cure® had funded in earlier filings.
  • No grants were paid directly to organisations outside the US.
  • <1% of grant dollars went to intermediaries that regrant to other organisations.

Grants

88 grants in the latest filing analysed · median $25,000

How much do they typically give?

Share of 88 grants in tax year 2025 by size

$1k–$2.5k9%
$2.5k–$5k2%
$5k–$10k19%
$10k–$25k16%
$25k–$50k7%
$50k–$100k18%
$100k–$250k20%
$250k–$500k6%
$500k–$1M1%
$1M and over1%

Median $25,000 (tax year 2025)

The largest grants to organisations in the foundation’s latest filing:

  • After-School All-Stars · Children in need.
    $1,300,0002025 tax year
  • Massachusetts General Hospital · Als research.
    $598,6682025 tax year
  • Big Dog Ranch · Animal rescue.
    $310,0002025 tax year
  • Team Gleason · Assist people with als and their family.
    $275,0002025 tax year
  • America First Policy Institute · Assist in non-partisan research.
    $250,0002025 tax year
  • American Society of the Italian Legions of Merit · Support men and women who have served in the us armed forces.
    $250,0002025 tax year
  • Massachusetts General Hospital · Als research.
    $250,0002025 tax year
  • Cedars-Sinai · Als research.
    $200,0002025 tax year

Grants to organisations listed in the foundation’s Form 990-PF filings. Grants to individuals are not shown.

Officers and directors

  • Babe Rizzuto — Trustee
  • Susan Rizzuto — Trustee
  • Denis Rizzuto — Trustee
  • Leandro Rizzuto — Trustee

From the latest Form 990-PF filing

3 years of tax filings

YearTotal expensesGrants paidAssetsFiling document
2023 tax year$7,624,235$7,726,917$47,098,326Filing for 2023 tax year
2024 tax year$13,459,415$13,606,263$49,697,958Filing for 2024 tax year
2025 tax year$7,386,540$7,301,468$50,418,882Filing for 2025 tax year

Figures from the foundation’s IRS Form 990-PF filings. Assets are at fair market value at year end. The document icon links to each year’s filing on ProPublica Nonprofit Explorer.

Sources

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